Spatial and Structural Metrics for Living Cells Inspired by Statistical Mechanics

Spatial and Structural Metrics for Living Cells Inspired by Statistical Mechanics

Experimental observations in cell biology have advanced to a stage where theory could play a larger role, much as it has done in the physical sciences. Possibly the lack of a common framework within which experimentalists, computational scientists and theorists could equally contribute has hindered this development, for the worse of both disciplines. Here we demonstrate the usage of tools and c...

Non-Equilibrium Statistical Mechanics Inspired by Modern Information Theory

A collection of recent papers revisit how to quantify the relationship between information and work in the light of modern information theory, so-called single-shot information theory. This is an introduction to those papers, from the perspective of the author. Many of the results may be viewed as a quantification of how much work a generalized Maxwell’s daemon can extract as a function of its ...

Planning for Protected Areas Using Spatial and Temporal Metrics

Statistical mechanics of spatial evolutionary games

We discuss the long-run behavior of stochastic dynamics of many interacting players in spatial evolutionary games. In particular, we investigate the effect of the number of players and the noise level on the stochastic stability of Nash equilibria. We discuss similarities and differences between systems of interacting players maximizing their individual payoffs and particles minimizing their in...

Mechanics of living cells measured by laser tracking microrheology.

To establish laser-tracking microrheology (LTM) as a new technique for quantifying cytoskeletal mechanics, we measure viscoelastic moduli with wide bandwidth (5 decades) within living cells. With the first subcellular measurements of viscoelastic phase angles, LTM provides estimates of solid versus liquid behavior at different frequencies. In LTM, the viscoelastic shear moduli are inferred from...